| Pick | Pitchers | Odds | Risk | To Win |
| Washington | Patrick Corbin / Dallas Keuchel | -110 | 5.5 | 5 |
| NY Yankees | Domingo German / Jhoulys Chacin | 100 | 4 | 4 |
| Chi. White Sox | Dillon Peters / Lucas Giolito | -145 | 4.35 | 3 |
| Arizona | Robbie Ray / Tyler Mahle | -115 | 3.45 | 3 |
| Minnesota | Adam Plutko / Michael Pineda | -170 | 3.4 | 2 |
| Chi. Cubs | Cole Hamels / Zach Davies | -120 | 2.4 | 2 |
| LA Dodgers | Jeff Samardzija / Clayton Kershaw | -245 | 2.45 | 1 |
| San Diego | Tim Melville / Dinelson Lamet | -165 | 1.65 | 1 |
| Miami | Jorge Lopez / Pablo Lopez | -126 | 1.26 | 1 |
| St. Louis | Miles Mikolas / Joe Musgrove | -120 | 1.2 | 1 |
| Texas | Brock Burke / Dylan Bundy | 115 | 0.87 | 1 |
| Philadelphia | Zach Eflin / Steven Matz | 135 | 0.74 | 1 |
| Toronto | Clay Buchholz / Brendan McKay | 170 | 0.59 | 1 |
| Seattle | Tommy Milone / Framber Valdez | 205 | 0.49 | 1 |
| Detroit | Spencer Turnbull / Homer Bailey | 220 | 0.45 | 1 |
