| Pick | Pitchers | Odds | Risk | To Win |
| NY Mets | Noah Syndergaard / Joe Ross | -105 | 5.25 | 5 |
| Houston | Gerrit Cole / Adrian Houser | -175 | 7 | 4 |
| Texas | Mike Minor / Masahiro Tanaka | 180 | 2.22 | 4 |
| Minnesota | Jake Odorizzi / Jordan Zimmermann | -200 | 4 | 2 |
| Cincinnati | Drew Smyly / Anthony DeSclafani | -137 | 2.74 | 2 |
| Atlanta | Jacob Waguespack / Mike Soroka | -260 | 2.6 | 1 |
| San Diego | Cal Quantrill / Mike Leake | 127 | 0.79 | 1 |
| San Francisco | Tyler Beede / Adam Wainwright | 160 | 0.63 | 1 |
| Chi. White Sox | Ross Detwiler / Aaron Civale | 215 | 0.47 | 1 |
| Baltimore | Asher Wojciechowski / Ryan Yarbrough | 250 | 0.4 | 1 |
| Seattle | Justus Sheffield / Kyle Hendricks | 250 | 0.4 | 1 |
| Colorado | Peter Lambert / Walker Buehler | 280 | 0.36 | 1 |
