| Pick | Pitchers | Odds | Risk | To Win |
| Baltimore | Dylan Bundy / Jorge Lopez | -120 | 3.6 | 3 |
| Chi. Cubs | Zach Davies / Cole Hamels | -150 | 3 | 2 |
| St. Louis | Pablo Lopez / Stephen Strasburg | -140 | 2.8 | 2 |
| Cleveland | Zach Plesac / Diego Castillo | -110 | 2.2 | 2 |
| Detroit | Martin Perez / Matthew Boyd | 122 | 1.64 | 2 |
| Houston | Framber Valdez / Clay Buchholz | -170 | 1.7 | 1 |
| LA Dodgers | Clayton Kershaw / Robbie Ray | -145 | 1.45 | 1 |
| Pittsburgh | Joe Musgrove / Tim Melville | -120 | 1.2 | 1 |
| NY Mets | Steven Matz / Jason Vargas | -115 | 1.15 | 1 |
| San Diego | Joey Lucchesi / Logan Webb | -105 | 1.05 | 1 |
| Oakland | Homer Bailey / Domingo German | 175 | 0.57 | 1 |
| Chi. White Sox | Reynaldo Lopez / Dallas Keuchel | 180 | 0.56 | 1 |
| Miami | Elieser Hernandez / Anibal Sanchez | 250 | 0.4 | 1 |
