| Pick | Pitchers | Odds | Risk | To Win |
| Miami | Danny Duffy / Caleb Smith | -115 | 3.45 | 3 |
| LA Angels | Andrew Heaney / Dylan Covey | -150 | 3 | 2 |
| Atlanta | Austin Voth / Julio Teheran | -140 | 2.8 | 2 |
| Tampa Bay | Anthony Kay / Charlie Morton | -260 | 2.6 | 1 |
| San Diego | Jeff Hoffman / Joey Lucchesi | -160 | 1.6 | 1 |
| St. Louis | Adam Wainwright / Steven Brault | -140 | 1.4 | 1 |
| Chi. Cubs | Yu Darvish / Gio Gonzalez | -130 | 1.3 | 1 |
| Texas | Jonathan Hernandez / Aaron Brooks | -105 | 1.05 | 1 |
| Boston | J.A. Happ / Travis Lakins | 105 | 0.95 | 1 |
| Arizona | Alex Young / Luis Castillo | 140 | 0.71 | 1 |
| Philadelphia | Drew Smyly / Marcus Stroman | 145 | 0.69 | 1 |
| Cleveland | Aaron Civale / Jake Odorizzi | 145 | 0.69 | 1 |
| San Francisco | Tyler Beede / Tony Gonsolin | 210 | 0.48 | 1 |
| Detroit | Jordan Zimmermann / Chris Bassitt | 250 | 0.4 | 1 |
| Seattle | Yusei Kikuchi / Justin Verlander | 320 | 0.31 | 1 |
