| Pick | Pitchers | Odds | Risk | To Win |
| Kansas City | Jakob Junis / Ivan Nova | 102 | 1.96 | 2 |
| Arizona | Zac Gallen / Zack Wheeler | 115 | 1.74 | 2 |
| Texas | Ryan Yarbrough / Lance Lynn | 120 | 1.67 | 2 |
| LA Dodgers | Walker Buehler / Ty Blach | -330 | 3.3 | 1 |
| Milwaukee | Chase Anderson / Elieser Hernandez | -175 | 1.75 | 1 |
| Atlanta | Max Fried / Jason Vargas | -162 | 1.62 | 1 |
| Boston | Nathan Eovaldi / T.J. Zeuch | -147 | 1.47 | 1 |
| St. Louis | Michael Wacha / Chi Chi Gonzalez | -145 | 1.45 | 1 |
| Chi. Cubs | Jose Quintana / Ronald Bolanos | -138 | 1.38 | 1 |
| Cincinnati | Trevor Bauer / Justus Sheffield | -130 | 1.3 | 1 |
| Cleveland | Zach Plesac / Jose Suarez | -127 | 1.27 | 1 |
| Pittsburgh | Mitch Keller / Johnny Cueto | 110 | 0.91 | 1 |
| Oakland | Tanner Roark / Wade Miley | 135 | 0.74 | 1 |
| Washington | Anibal Sanchez / Jose Berrios | 140 | 0.71 | 1 |
