| Pick | Pitchers | Odds | Risk | To Win |
| Texas | Lance Lynn / Chad Green | 140 | 3.57 | 5 |
| San Francisco | Madison Bumgarner / Michael Wacha | 110 | 3.64 | 4 |
| Philadelphia | Aaron Nola / Trevor Bauer | -130 | 2.6 | 2 |
| NY Mets | Zack Wheeler / Anibal Sanchez | 115 | 1.74 | 2 |
| Minnesota | Jose Berrios / Eduardo Rodriguez | 121 | 1.65 | 2 |
| LA Dodgers | Antonio Senzatela / Hyun-Jin Ryu | -360 | 3.6 | 1 |
| San Diego | Chris Paddack / Zac Gallen | 125 | 0.8 | 1 |
| LA Angels | Patrick Sandoval / Tanner Roark | 145 | 0.69 | 1 |
| Miami | Robert Dugger / Trevor Williams | 170 | 0.59 | 1 |
| Detroit | Edwin Jackson / Jakob Junis | 190 | 0.53 | 1 |
| Chi. White Sox | Ivan Nova / Shane Bieber | 245 | 0.41 | 1 |
