Analysis of Arizona Cardinals vs Buffalo Bills Week 1 2024

Buffalo Bills Offense

The Buffalo Bills enter the 2024 season with several key changes to their offense. Despite the departure of Stefon Diggs and Gabe Davis, they have bolstered their receiving corps with Curtis Samuel and rookie Keon Coleman. Josh Allen remains the cornerstone of their offense, and his ability to perform as a dual-threat quarterback is well-documented. The Bills' offensive line is expected to be solid, which should help in both pass protection and run blocking. With James Cook potentially seeing more action, the Bills' running game could be a significant factor.

Arizona Cardinals Offense

The Arizona Cardinals are looking to capitalize on the health of Kyler Murray, who has been plagued by injuries in the past. Murray's dynamic playmaking ability, combined with the addition of Marvin Harrison Jr., the fourth overall pick in the draft, gives the Cardinals a promising offense. James Conner and Trey Benson provide a strong running back duo, and the Cardinals' passing game could see significant improvements if Murray stays healthy.

Defensive Matchups

The Cardinals' defense is a major question mark, particularly in the secondary. While they have added new cornerbacks like Max Melton and Shawn Murphy-Bunting, their pass defense was rough last year. The Bills, on the other hand, have a more established defense that was hampered by injuries last season. With Matt Milano back and Terrel Bernard stepping up, the Bills' defense looks more solid. However, the Bills will need to contend with the Cardinals' improved offense, especially if Murray can exploit their secondary.

Betting Trends and Home Advantage

The Bills have a strong home record against NFC opponents, having won 10 of their last 11 home games. They also have a favorable trend in September games, covering the spread in 10 of their last 11 against NFC opponents. The Cardinals, however, have struggled against AFC opponents, losing seven of their last eight games.

Our Prediction

Given the analysis, the Bills' home advantage, and their historical trends against NFC opponents, it seems likely that the Bills will cover the spread.

Our Prediction – Buffalo Bills (-5.5)

The Bills' offense, led by Josh Allen, should be able to outperform the Cardinals' defense, which is still unproven. While the Cardinals' offense has potential, the Bills' defense is more established and should be able to limit the damage. The Bills' recent form and betting trends also support this pick.