- Louisville at Wake Forest – Wake Forest (+2.5)
- Demon Deacons are 6-0-1 ATS in their last 7 games following a ATS loss.
- Demon Deacons are 3-0-1 ATS in their last 4 home games.
- Demon Deacons are 7-2-1 ATS in their last 10 conference games.
- Demon Deacons are 8-3-1 ATS in their last 12 games overall.
- Demon Deacons are 5-2 ATS vs. a team with a winning record.
- Cardinals are 2-10 ATS in their last 12 games overall.
- Cardinals are 0-3-1 ATS in their last 4 games following a ATS win.
- Cardinals are 0-6 ATS vs. a team with a winning record.