Spread
| Matchup | Public Pick – Spread |
| Oakland at Houston | 68% on Houston (-4) |
| Miami at Pittsburgh | 64% on Miami (+10) |
| Detroit at Seattle | 62% on Detroit (+8) |
| New York Giants at Green Bay | 51% on Green Bay (-4.5) |
Moneyline
| Matchup | Public Pick – ML |
| Miami at Pittsburgh | 94% on Pittsburgh (-480) |
| New York Giants at Green Bay | 71% on Green Bay (-210) |
| Oakland at Houston | 66% on Houston (-200) |
| Detroit at Seattle | 58% on Detroit (+305) |
Total
| Matchup | Public Pick – Total |
| New York Giants at Green Bay | 78% on Over 44.5 |
| Detroit at Seattle | 71% on Over 42.5 |
| Miami at Pittsburgh | 64% on Over 46.5 |
| Oakland at Houston | 61% on Under 36.5 |