Spread
| Matchup | Public Pick – Spread |
| Pittsburgh at Buffalo | 95% on Pittsburgh (-1) |
| Atlanta at Los Angeles | 95% on Atlanta (-6) |
| Minnesota at Jacksonville | 92% on Minnesota (-3.5) |
| Washington at Philadelphia | 88% on Washington (pk) |
| Denver at Tennessee | 88% on Denver (+1) |
| Cincinnati at Cleveland | 88% on Cincinnati (-5.5) |
| Houston at Indianapolis | 84% on Indianapolis (-6) |
| San Diego at Carolina | 80% on Carolina (-1) |
| New Orleans at Tampa Bay | 77% on Tampa Bay (-2.5) |
| Chicago at Detroit | 77% on Detroit (-7.5) |
| Arizona at Miami | 77% on Arizona (+1) |
| New York Jets at San Francisco | 70% on New York Jets (+3) |
| Dallas at New York Giants | 62% on Dallas (-3) |
| Seattle at Green Bay | 58% on Green Bay (+3) |
| Oakland at Kansas City | 51% on Kansas City (-3) |
| Baltimore at New England | 50% on New England (-7) |
Moneyline
| Matchup | Public Pick – ML |
| Houston at Indianapolis | 99% on Indianapolis (-260) |
| Cincinnati at Cleveland | 97% on Cincinnati (-245) |
| Dallas at New York Giants | 94% on New York Giants (+155) |
| Minnesota at Jacksonville | 88% on Minnesota (-175) |
| Pittsburgh at Buffalo | 85% on Pittsburgh (-125) |
| Baltimore at New England | 80% on New England (-330) |
| Washington at Philadelphia | 75% on Washington (+100) |
| New Orleans at Tampa Bay | 75% on Tampa Bay (-145) |
| San Diego at Carolina | 75% on San Diego (+110) |
| New York Jets at San Francisco | 75% on New York Jets (+130) |
| Atlanta at Los Angeles | 75% on Atlanta (-260) |
| Arizona at Miami | 75% on Arizona (-105) |
| Denver at Tennessee | 74% on Tennessee (+100) |
| Chicago at Detroit | 73% on Chicago (+280) |
| Seattle at Green Bay | 67% on Seattle (-150) |
| Oakland at Kansas City | 57% on Oakland (+140) |
Total
| Matchup | Public Pick – Total |
| Chicago at Detroit | 94% on Over 43.5 |
| Minnesota at Jacksonville | 91% on Under 39.5 |
| Washington at Philadelphia | 84% on Over 47 |
| Denver at Tennessee | 75% on Under 43.5 |
| New York Jets at San Francisco | 75% on Under 43.5 |
| Houston at Indianapolis | 75% on Over 47 |
| Seattle at Green Bay | 74% on Under 46 |
| San Diego at Carolina | 69% on Over 48 |
| Cincinnati at Cleveland | 61% on Under 43 |
| Baltimore at New England | 60% on Under 45 |
| Oakland at Kansas City | 59% on Under 46 |
| Arizona at Miami | 58% on Under 43 |
| Atlanta at Los Angeles | 58% on Over 45 |
| New Orleans at Tampa Bay | 56% on Under 51.5 |
| Pittsburgh at Buffalo | 55% on Over 46.5 |
| Dallas at New York Giants | 53% on Under 47.5 |