After all these years, the legion of boom still commands respect in the secondary. What do you think Fitzpatrick is dreaming about this week after just throwing 6 picks last week? Could get ugly.
Best Defense to Start in 2016 NFL Week 4
| Name | Salary | GameInfo | Matchup DVOA |
| Seahawks | 3800 | Sea@NYJ 01:00PM ET | -48.9 |
| Cardinals | 3900 | LARM@Ari 04:25PM ET | -42.8 |
| Titans | 2400 | Ten@Hou 01:00PM ET | -30.4 |
| Chiefs | 3000 | KC@Pit 08:30PM ET | -26.7 |
| Vikings | 3600 | NYG@Min 08:30PM ET | -25.6 |