Giants just came off their best running game of the season against the Bengals defense. McCoy will get to go up against this 24th ranked rushing defense.
Best Running Back to Start in 2016 NFL Week 11
| Name | Salary | GameInfo |
| LeSean McCoy | 6900 | Buf@Cin 01:00PM ET |
| Le’Veon Bell | 8800 | Pit@Cle 01:00PM ET |
| Latavius Murray | 5500 | Hou@Oak 08:30PM ET |
| DeMarco Murray | 8200 | Ten@Ind 01:00PM ET |
| Jay Ajayi | 6800 | Mia@LARM 04:05PM ET |