| Pick | Pitchers | Odds | Risk | To Win |
| Washington | Stephen Strasburg / Martin Perez | -145 | 5.8 | 4 |
| San Francisco | Dario Agrazal / Logan Webb | -110 | 3.3 | 3 |
| Chi. White Sox | Glenn Sparkman / Reynaldo Lopez | -160 | 3.2 | 2 |
| St. Louis | Dakota Hudson / Antonio Senzatela | -136 | 2.72 | 2 |
| Cleveland | Adam Plutko / Dillon Peters | -130 | 2.6 | 2 |
| Arizona | Robbie Ray / Steven Matz | 100 | 2 | 2 |
| LA Dodgers | Ross Stripling / John Means | -180 | 1.8 | 1 |
| Boston | Bobby Poyner / Wilmer Font | -150 | 1.5 | 1 |
| Milwaukee | Zach Davies / Pablo Lopez | -143 | 1.43 | 1 |
| Cincinnati | Sonny Gray / Marco Gonzales | -142 | 1.42 | 1 |
| Atlanta | Dallas Keuchel / Zach Eflin | -130 | 1.3 | 1 |
| Chi. Cubs | Cole Hamels / Chris Paddack | -105 | 1.05 | 1 |
| Detroit | CC Sabathia / Matthew Boyd | 180 | 0.56 | 1 |
